Key Facts
- ✓ Geneticists discovered Yersinia pestis genes in ancient human DNA samples.
- ✓ An epidemic raged in Eurasia five thousand years ago, predating the Justinianic plague by 3,500 years.
- ✓ The discovery challenges the belief that zoonotic diseases emerged primarily with the invention of agriculture 12,000 years ago.
- ✓ Large-scale outbreaks occurred in Europe approximately 5,000 years ago.
Quick Summary
Historians and geneticists are re-evaluating the timeline of human infectious diseases following a significant discovery. Analysis of ancient human DNA samples revealed the presence of genes belonging to the Yersinia pestis bacteria, indicating a massive epidemic occurred in Eurasia five thousand years ago.
This timeline places the outbreak nearly 3,500 years before the so-called 'first plague,' known as the Justinianic plague. The findings suggest that the transition of diseases from animals to humans occurred much later than previously thought, contradicting the established view that this shift happened immediately following the invention of agriculture.
Genetic Evidence of a Prehistoric Epidemic
Researchers studying the history of disease have encountered a paradigm-shifting problem. Through the examination of ancient human DNA, geneticists identified specific markers associated with the plague bacterium Yersinia pestis. This evidence confirms that a virulent epidemic was raging across Eurasia approximately 5,000 years ago.
The discovery predates the Justinianic plague—which is named after the ruling Roman emperor of the time—by a significant margin of 3,500 years. This ancient outbreak is currently the subject of intense study, often referred to by the technical label Late Neolithic-Bronze Age (LNBA) plague.
Challenging Established Theories
For decades, the prevailing scientific consensus held that zoonotic diseases—illnesses that jump from animals to humans—emerged largely as a result of the agricultural revolution roughly 12,000 years ago. The new genetic findings, however, suggest that this critical evolutionary leap occurred much later in human history.
The data indicates that large-scale outbreaks were not a feature of early agricultural societies but rather appeared thousands of years later. This discovery serves as a major blow to the long-held belief regarding when and why humanity acquired the infectious diseases that affect us today.
A Gallery of Prehistoric Horrors
As scientists delve deeper into the genetic record of the past, they are uncovering what has been described as a 'gallery of prehistoric horrors.' These findings are forcing a re-evaluation of a pivotal prehistoric period.
The emergence of these pathogens raises critical questions about the dynamics of disease transmission in antiquity. Did pathogens act similarly to how they do today? Furthermore, there is speculation regarding the role the plague may have played in shaping the Bronze Age and laying the foundations for European civilization.
Implications for Human History
The identification of the LNBA plague does more than just adjust a date on a timeline; it fundamentally alters our understanding of human evolution and societal development. By pushing back the timeline of major zoonotic events, researchers are forced to look at the transition to the Bronze Age through a new lens.
If the plague was indeed a driving force during this era, it suggests that biological factors played a much larger role in the collapse of old orders and the rise of new civilizations than previously credited. The Justinianic plague is no longer the starting point for the history of plague in the region; the roots are far deeper and more complex.




